Martiderm ampoules: 5 best pharmacy products in 2026
What defines a quality cosmetic ampoule
Martiderm ampoules are single-dose cosmetic vials that deliver concentrated active ingredients to the skin using a stabilised, usually liposomal, solution. Not all ampoules are the same, and in pharmacy we know this well. A quality ampoule is not just the one that smells nice or has attractive packaging: it is the one that uses a delivery system capable of taking the actives to where they need to work. In the case of Martiderm, its liposomal technology encapsulates the active ingredients in phospholipid vesicles that fuse with the cell membrane and release the active in deeper layers of the epidermis. That makes a real difference compared with conventional aqueous formulas.
The concentration of active also matters, as does formulation stability — especially for vitamin C and oxidisable depigmenting agents — the absence of fragrance in treatment formulas, and having efficacy studies that are clinically validated. Martiderm publishes its evidence and has worked with dermatologists since it was founded in Barcelona; that gives me enough confidence to recommend these products without hesitation.
- Martiderm ampoules use liposomal technology to deliver active ingredients into deeper epidermal layers than standard aqueous solutions.
- Stability of vitamin C and other oxidisable actives is critical for ampoule efficacy over their full period of use.
- Fragrance-free treatment formulas and published clinical data are key quality markers for cosmetic ampoules.
Selection criteria
To create this list I have applied the same criteria I use in the pharmacy: efficacy backed by studies or well-documented mechanisms of action, safety of the ingredient profile, price-to-quantity ratio, suitability for different skin types and real availability on Farma2Go. I have ruled out products with unnecessary fragrance in treatment formulas and prioritised those I dispense most often because patients come back to ask for them again, which is the best indicator I know.
- I prioritise Martiderm products with documented mechanisms of action and good clinical or real-world efficacy signals.
- Ingredient safety, value for money and suitability for different skin types guide my product selection.
- Repeat purchase behaviour from patients is a practical indicator of how well a product performs.
How to add it to your routine
Gentle cleansing as a base
Before applying any ampoule, cleanse your face with a neutral or slightly acidic pH cleanser. Clean skin absorbs liposomal actives up to around 40% better than skin with traces of make-up or sebum. Do not use very hot water: it dilates capillaries and can increase irritation in reactive skin.
Ampoule on slightly damp skin
Open the ampoule and apply it by gently patting over face and neck. Slightly damp skin helps diffusion of the liposomal phospholipids. Use a full ampoule per application to ensure you get the correct concentration of actives each time.
Wait 2–3 minutes before the next step
Let the ampoule absorb before applying your cream or SPF. This short pause makes a real difference to perceived efficacy. Use it to apply eye contour if you use one.
Daily sun protection is non‑negotiable
If you use Pigment Zero or Photo Age HA+ in the morning, sun protection is not optional: it is part of the treatment. Without at least SPF 30, depigmenting actives and retinol work at half speed. I strongly recommend SPF even on cloudy days when you are choosing the best Martiderm routine for hyperpigmentation.
Mask as a weekly ritual
Add Moisturising Mask once or twice a week as the last step in your night-time routine. Apply it after your usual ampoule and leave it on for 20 minutes. Remove any excess without rinsing. The effect the next day is immediate and very satisfying, especially if you are combining Martiderm with other anti-ageing skincare.
- Cleansing with a gentle, slightly acidic product improves penetration of actives from Martiderm ampoules.
- Applying an entire single-dose ampoule ensures you receive the intended concentration of ingredients per use.
- Daily broad-spectrum SPF 30 or higher is essential when using brightening or retinoid-based Martiderm treatments.
Pharmacist recommendations
I have been dispensing Martiderm ampoules for years and I can say, quite plainly, that their continued presence on pharmacy shelves is no accident: they work because they are well formulated, with genuine liposomal technology and actives at effective concentrations. What I tell my patients most often is that the most important factor in results is not which specific ampoule they choose, but how consistently they use it. A box of 30 ampoules means 30 days of treatment; that is the minimum time you need before you start judging objective results from any Martiderm skincare routine.
If you are unsure which of these ampoules fits your skin or current routine best, write to me via the Farma2Go chat or leave me a comment: I prefer to support each person with a personalised recommendation rather than a generic answer. Your skin is your largest organ; it deserves to be treated well.
Comparativa ampollas Martiderm
| Producto | Objetivo principal | Momento de uso | Ideal para |
|---|---|---|---|
| Pigment Zero | Despigmentante | Mañana o noche | Manchas y tono desigual |
| Proteoglicanos | Antiedad estructural | Noche | Firmeza y densidad de piel |
| Photo Age HA+ | Hidratación + antioxidante | Mañana | Piel deshidratada, exposición a pantallas |
| Moisturising Mask | Hidratación intensiva semanal | 1-2 veces/semana | Refuerzo puntual de rutina |
Frequently asked questions
Scientific references
