Is cosmetic PDRN the same as injectable Rejuran?

Not exactly. The active is the same, but the injectable is introduced into the dermis at high concentration by a healthcare professional, producing faster and stronger effects. Topical cosmetic PDRN penetrates less but has cumulative effects at 8-12 weeks. Complementary.

How long does topical PDRN take to show?

Hydration and radiance: 1-2 weeks. Barrier repair: 2-4 weeks. Firmness, fine lines: 8-12 weeks. Scars and residual marks: 12-24 weeks.

Yes. One of the best cosmetic safety profiles: no irritation, no photosensitisation. Only real precaution: allergy to fish or salmon sperm in highly sensitised people, very rare due to purification of the active.

Can PDRN be used during pregnancy?

Topical cosmetic generally considered safe, check with your gynaecologist particularly in formulations with many associated actives. Injectable versions contraindicated in pregnancy and breastfeeding.

Which actives combine well with PDRN?

Almost all. Synergistic with peptides, hyaluronic acid, ceramides, centella, niacinamide. Compatible with retinol on alternating nights. No conflicts with vitamin C or acids.

Does the price of PDRN justify its efficacy?

For specific indications (post-procedure, advanced anti-ageing, residual marks) yes. For basic daily hydration, more accessible actives (hyaluronic acid, niacinamide) cover most needs.

PDRN | Premium regenerating serums | Farma2Go

PDRN

Pharmacy serums, ampoules and treatments with PDRN (polydeoxyribonucleotide). DNA fragments extracted from salmon sperm with high affinity for skin A2A adenosine receptors. They can stimulate cell regeneration, collagen synthesis and skin barrier repair. It is one of the most advanced clinical actives in Korean skincare, with parallel use in injectable aesthetic medicine (Rejuran). Concentrations from 0.5% to 5% in OTC skincare.