Refordog 400 mg/2000 mg in spot-on format (4 pipettes) is designed for dogs weighing 25–40 kg. It combines imidacloprid and permethrin to act quickly and conveniently against fleas (Ctenocephalides canis and C. felis), masticator lice (Trichodectes canis), and ticks; provides protection against fleas and Rhipicephalus sanguineus and Ixodes ricinus for up to 4 weeks, against Dermacentor reticulatus for up to 3 weeks, and also reduces the risk of Ehrlichia canis transmission.
It also offers a repellent/anti-feeding effect against phlebotomine sandflies (Phlebotomus papatasi for 2 weeks, Phlebotomus perniciosus for 3 weeks) and helps reduce the risk of Leishmania infantum infection for up to 3 weeks; applied topically, it does not require a prescription, and is marketed under the brand Alivira (Karizoo). Additionally, it is indicated for the treatment of external otitis of bacterial and fungal origin.
